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Definition and Significance of Mutation

108. determin...

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108. determine the sequence of genes along a chromosome based on the following recombination frequencies : A-B=8% ,A-C=28% , A-D= 25%, B-C=20%, B-D=33%. (a.)ABCD (b)BADC (c)CDBA (d)DA

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Q. A scientist performed the gene mapping experiments in maize. He mapped the genes on chromosomes on the basis of % crossing over between different genes. One map unit corresponds to one % crossing over or recombination. The genes showing more than 50% recombination were not supposed to be linked on same chromosome. In crossing over studies on maize, scientist observed the following % crossing over between genes A, B, C, D: between A and D 10%, between A and C 3%, between genes C and D 7%, between genes A and B 5%, and between genes C and B 8%. On the basis of above observation, find out the correct sequence of genes A, B, C and D on chromosomes.

Q. How many of the following statements are correct?
Statement I: Recombination of genes is directly proportional to the strength of linkage.
Statement II: Recombination of genes is inversely proportional to the strength of linkage.
Statement III: More the distance between the two genes on a chromosome, less the strength of linkage.
Statement IV: More the distance between the two genes on a chromosome, more the strength of linkage.
Statement V: Recombination frequency is inversely proportional to the distance between the genes present on a chromosome.

Q. The frequency of recombination between genes present on the same chromosome as a measure of the distance between genes was explained by:

Q. Who used in frequency of recombination between gene pairs on the same chromosome as a measure of distance between genes and mapped their position on chromosome.

Q. There are three genes a, b, c. Percentage of crossing over between a and b is 20%, b and c is 28% and a and c is 8%. What is the sequence of genes on chromosome?

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Definition and Significance of Mutation

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