The correct option is
D 12,16,8,13The given group of numbers follow a pattern :
The first three numbers form an horizontal straight line and fourth number form vertical straight line when joined with third number in the group.
Also, the next group of number starts with the number which is just above and right to the first number of previous group.
Thus, the missing term starts with 12 then 16,8 to form straight horizontal line and then 13 to form vertical straight line with 8.
Hence, the missing group of numbers is 12,16,8,13.