Question

$5^{\prime }-ACT-3^{\prime }$

The anticodon that will bind to the above given codon is

• A. $3^{\prime }-ACU-5^{\prime }$
• B. $3^{\prime }-TGA-5^{\prime }$
• C. $3^{\prime }-UGA-5^{\prime }$
• D. $5^{\prime }-ACU-3^{\prime }$
• E. $5^{\prime }-UGA-3^{\prime }$

Answer 1

The correct option is C $3^{\prime }-UGA-5^{\prime }$

The mRNA codon is read in 5’ to 3’ direction. Alignment of the mRNA and tRNA is antiparallel which means that 5’ end of mRNA pairs with 3’ end of tRNA. The first base of the codon in mRNA (read in the 5’ to 3’direction) pairs with the third base of the anticodon thus the codon 5'-ACT-3' would pair with 3'-UGA-5' anticodon. Thus, the correct answer is option C.