6. During nucleophilic reactions of alcohol why is partial positive and negative charge not develpoed between carbon and oxygen It is always seen between oxygen and hydrogen like in the reaction of Alcohol and Grignard reagent

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Q. What type of attraction occurs between the partial positively charged hydrogen atom in one water molecule and the partial negatively charged oxygen atom in another water molecule?

Q. Primary alcohols are obtained by the reaction of Grignard reagent with:

Show how are the following alcohols prepared by the reaction of a suitable Grignard reagent and aldehyde/ketone?

The most characteristic reaction of aldehyde and ketones is nucleophilic addition to carbon oxygen double bond. Aldehyde and ketones are easily susceptible to nucleophilic addition because of structural features. The trigonal planar arrangement of groups around the carbonyl carbon atom means that the carbonyl carbon atom is relatively open to attack from above and below the plane of carbonyl group. The partial positive charge on the carbonyl atom means that it is especially susceptible to attack by a nucleophile

Oximes are formed by the reaction of aldehyde or ketones with

Grignard reagent is usually prepared by :

R - X + M g E t_{2} O - -- \to R M g X

Grignard reagent

A r - X + M g E t_{2} O - -- \to A r M g X

Grignard reagent

Grignard reagent acts as a strong base. Grignard reagent carry out nucleophilic attack in absence of acidic hydrogen. Grignard reagent form complex with its ether solvent. Complex formation with molecule of ether is an important factor in the formation and stability of Grignard reagent.

Which of the following Grignard reagents are not possible ?

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