Klinefelter Syndrome

Q. Match the contents of column I, II and III.
$\begin{array}{ccc}\text{Column I}& \text{Column II}& \text{Column III}\\ \text{1.Albinism}& \text{i) Sterile woman}& \text{a) 44+XXY}\\ \text{2.Sickle-cell anaemia}& \text{ii) Sterile man}& \text{b) Trisomy of 21st chromosome}\\ \text{3.Klinefelter syndrome}& \text{iii) Reduced}{\text{O}}_2\text{carrying capacity}& \text{c) Monosomy of X chromosome}\\ \text{4.Down syndrome}& \text{iv) Pink eyes}& \text{d) Loss of pigmentation}\\ \text{5.Turner syndrome}& \text{v) Single palm crease}& \text{e) Presence of valine instead of glutamic acid}\end{array}$

1. 1-iv-d, 2-iii-e, 3-ii-a, 4-v-b, 5-i-c
2. 1-v-d, 2-iii-a, 3-ii-e, 4-iv-b, 5-i-c
3. 1-iii-d, 2-iv-e, 3-ii-a, 4-v-c, 5-i-b
4. 1-iv-c, 2-i-e, 3-ii-a, 4-v-b, 5-iii-c

Q.

What will be the blood groups of offsprings produced by the parents having following Male-I^AI^B & Female-I^OI^A genotype? Draw a punnet square and write the phenotype and genotype ratio. [3 MARKS]

Q.

Assertion [A]: Klinefelter syndrome occurs only in males.

Reason [R]: Klinefelter syndrome is characterised by an additional Y chromosome in the karyotype.

1. R is true and A is false
2. Both A and R are true and R is the correct explanation for A
3. Both A and R are true but R is not the correct explanation for A
4. A is true and R is false

Q. The genotype of a person suffering from Klinefelter's syndrome is .

1. 44+XYY
2. 44+XXY
3. 44+XO

Q. Direction: Choose the correct option:

Assertion (A): Cross breeding of dairy animals increases the productivity of milk.
Reason (R): Lactation period of dairy animals can be increased by cross breeding.

Q.

Choose the correct option:

Assertion [A]: Patients having Klinefelter syndrome have higher amounts of estrogen in the body.
Reason [R]: Klinefelter syndrome occurs due to appearance of an extra X chromosome in the human males.

1. Assertion [A] is True and Reason [R] is False.

2. Reason [R] is True and Assertion [A] is False.

3. Assertion [A] is True and Reason [R] is True and is a correct explanation for [A].

4. Assertion [A] is True and Reason [R] is True but is an incorrect explanation to [A].

Q.

Klinefelter’s syndrome is represented as:

1. 44 + XO

2. 45 + XY

3. 44+ XXY

4. 66 + XXY

Q. Assertion [A]: Patients suffering from Klinefelter's syndrome have high amounts of estrogen secreted in their body.

Reason [R]: Klinefelter's syndrome occurs due to the presence of an extra X chromosome in human males.

1. A is True and R is False
2. R is True and A is False
3. Both A and R are true and R is a correct explanation for A
4. Both A and R are true but R is not a correct explanation to A

Q. Why people with klinefelter syndrome and turner's syndrome are sterile?

Q. Number of Barr bodies in human female suffering from Down's Syndrome would be

1. 3
2. 2
3. Zero
4. 1

Q. An individual affected by Klinefelter’s syndrome would be a:

1. Sterile female
2. Fertile female
3. Fertile male
4. Sterile male

Q. Posterior end of male Enterobius possesses

1. One penial spicule
2. Two equal penial spicules
3. Two unequal penial spicules
4. None of the above

Q. Assertion :$H{b}^{c}H{b}^{S^C}$, is homozygous condition of sickle cell anaemia. Reason: It occurs due to substitution of glutamic acid by valine at 6th position of $\beta$-chain of haemoglobin.

1. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
2. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
3. Assertion is correct but Reason is incorrect
4. Both Assertion and Reason are incorrect

Q. cite the difference between Downs syndrome and Turners syndrome

Q. Assertion :Only a boy child could be born with the substitution of glutamic acid by valine on 6th position $\beta$-chain of haemoglobin. Reason: The gene for the above mutation occurs in Y-Chromosome.

1. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
2. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
3. Assertion is correct but Reason is incorrect
4. Both Assertion and Reason are incorrect

Q. Tay-Sach disease is due to

1. Sex-linked recessive gene
2. Autosomal dominant gene
3. Sex-linked dominant gene
4. Autosomal recessive gene