Shape of RBC

Q. Sickle cell anemia is due to

1. Change of amino acid in alpha chain of hemoglobin
   
2. Change of the amino acid in beta chain of hemoglobin
3. Change of amino acid in both alpha and beta chain of hemoglobin
4. Change of amino acid either alpha or beta chain of hemoglobin

Q.

The cell maintain Homeostasis.What do you understand by homeostasis and why does the cell maintain it?

Q. Which of the following is not a function of Rough endoplasmic Reticulum? (1 mark)


A. Provides a surface for ribosomes
B. Surface for protein synthesis
C. Involved in post-translational modification of proteins
D. Calcium storage

Q. Adult human RBCs are enucleated. Which of the following statement(s) is/are the most appropriate explanation for this feature?
(a) They do not need to reproduce
(b) They are somatic cells
(c) They do not metabolise
(d) All their internal space is available for oxygen transport

1. Only (a)
2. (a), (c) and (d)
3. (b) and (c)
4. only (d)

Q. State three main differences between the smooth and rough endoplasmic reticulum.

Q. Inadequate protein intake leads to Kwashiorkor . The subsequent oedema is most closely related to inadequate synthesis of which protein ?

1. Gamma globulin
2. Glucagon
3. Insulin
4. Albumin

Q. Examination of the blood of a person suspected of having anemia shows large, immature, nucleated erythrocytes without hemoglobin. supplementing his diet with which of the following is likely to alleviate his symptoms?

1. Thiamine
2. Folic acid and cobalamin
3. Riboflavin
4. Iron compounds

Q.

Assertion (A) – RBCs are circular and biconcave in shape lacking all cell organelles.

Reason (R) - Circular and biconcave shape increase the surface area for oxygen binding and the lack of organelles results in no self-utilisation of the oxygen being carried.

1. Both A and R are correct and R is the correct explanation of A.

2. A is correct but R is wrong

3. A is wrong but R is correct

4. Both A and R are wrong

Q. Absence of phenylalanine hydroxylase in liver produces a disease called __________.

1. Alkaptonuria
2. Phenylketonuria
3. G$6$-PD deficiency
4. Duchenne's muscular dystrophy