Gene Therapy
Trending Questions
Q. The most popular vector used in human gene therapy is
- Plasmid
- Phage
- PUC 18
- Retrovirus
Q.
The genetic defect - Adenosine Deaminase (ADA) deficiency may be cured permanently by
periodic infusion of genetically engineered lymphocytes having functional ADA C-DNA
administering adenosine deaminase activators
introducing bone marrow cells producing ADA into cells at early embryonic stages
enzyme replacement therapy
Q. The first clinical gene therapy was done for the treatment of
- AIDS
- Cancer
- Cystic fibrosis
- SCID
Q. A scientist used a plasmid that contained ampicillin resistance gene and lacZ gene as selectable markers. He inserted the gene of interest within the ampicillin resistance gene instead of lacZ gene due to human error. The competent cells were allowed to take up the plasmid. This was followed by plating them on agar media containing ampicillin and X-gal. Which of the following statements correctly describes the result of the experiment?
- The bacteria which took up the recombinant plasmid would not grow
- The bacteria which took up the recombinant plasmid would form white colonies
- All of the bacteria would grow and give white colonies
- The bacteria which took up the recombinant plasmid would grow and give blue colonies
Q. Which of the following processes/techniques can be included under biotechnology?
- Correcting a defective gene
- All of these
- Synthesising a gene
- Developing a DNA based vaccine
Q. The gene of interest (GOI) is inserted at the
BamH I site in pBR322. The resulting plasmid is introduced into bacteria. The bacteria will have resistance against which of the following antibiotics?
BamH I site in pBR322. The resulting plasmid is introduced into bacteria. The bacteria will have resistance against which of the following antibiotics?
- Both a and b
- Tetracycline
- Streptomycin
- Ampicillin