Application in Medicine
Trending Questions
Q. Which one of the following can be used as a permanent cure for ADA deficiency?
- Bone marrow transplantation upon detection of disorder in adult
- Enzyme replacement therapy at any point in life
- Both a and b
- Gene therapy at early embryonic stages
Q. Gene therapy cures:
- Genetic disorders
- Nutritional defects
- Cataract
- Skin disorders
Q. Arrange the following steps of gene therapy for ADA deficiency in the correct sequence.
I) Infection of lymphocytes by genetically engineered retrovirus
II) Culture of lymphocytes
III) Isolation of lymphocytes from ADA deficient patient
IV) Genetically modified lymphocytes are injected back to patient
I) Infection of lymphocytes by genetically engineered retrovirus
II) Culture of lymphocytes
III) Isolation of lymphocytes from ADA deficient patient
IV) Genetically modified lymphocytes are injected back to patient
- II, III, I, IV
- III, I, II, IV
- I, II, III, IV
- III, II, I, IV
Q. If a person is born with a hereditary disease, can a corrective therapy be taken for such a disease?
Q.
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Q. Insulin is produced by the __________ cells of ______.
- alpha cells, liver
- beta cells, pancreas
- delta cells, pancreas
- F cells, liver
Q. Ramesh has undergone organ transplantation. In order to avoid failure of the transplant or organ rejection, which of the following can be prescribed to him?
- Cyclosporin A
- Statins
- Streptokinase
- Lipase
Q.
How many statements regarding ADA deficiency are correct?
- It is caused by insertion of a base in the sequence of ADA gene.
- ADA deficiency causes decreased concentration of lymphocytes in blood.
- Enzyme replacement therapy is just a one time injection.
- One of the major limitations of bone marrow transplantation is the lack of suitable donors.
- 1
- 3
- 4
- 2
Q.
Refer the internet and find out how to make orally active protein pharmaceutical. What is the major problem to be encountered?
Q. Pick the hormone which is not secreted by human placenta.
- HCG
- Prolactin
- Oestrogen
- HPL
Q. Enzyme streptokinase obtained from bacteria Streptococcus is used clinically as:
- α1 - antitrypsin in case of emphysema
- Food supplement by astronaut
- Surfactant in case of atelectasis
- Clot buster in case of myocardial infarction
Q. Hepatitis - B vaccine is
- First generation vaccine
- Second generation vaccine
- Third generation vaccine
- Fourth generation vaccine
Q. Vaccines prepared through recombinant DNA technology are called ________.
- First generation vaccines
- Second generation vaccines
- Third generation vaccines
- All of these above
Q. Which result is false according to Griffith's experiment?
- S Strain → Mice die
- R strain → Mice live
- S Strain(Heat killed) → Mice live
- S Strain(Heat killed) + R Strain(Live)→ Mice live
Q. Mtach the terms given in column 'A' with those in column 'B'.
Match the items given in column A with that given in column'B.
Match the items given in column A with that given in column'B.
Column A | Column B | ||
(a) | milk secretion | (i) | luteinising hormone |
(b) | glucocorticoids | (ii) | diabetes mellitus |
(c) | child birth | (iii) | thyroxine |
(d) | aldosterone | (iv) | prolactin |
(e) | cretinism | (v) | oxytocin |
(f) | insulin | (vi) | growth hormone |
(g) | spermatogenesis | (vii) | ACTH |
(h) | ovulation | (viii) | FSH |
(i) | vasopressin | (ix) | sodium metabolism |
(j) | acromegaly | (x) | diabetes insipidus |
Q. Maximum application of animal cell culture technology today is in the production of:
- Insulin
- Interferons
- Vaccines
- Edible proteins
Q. The genetic defect Adenosine Deaminase (ADA) deficiency may be cured permanently by
- periodic infusion of genetically engineered lymphocytes having functional ADA producing cDNA
- administering adenosine deaminase activators
- introducing the normal gene producing ADA into cells at early embryonic stage
- enzyme replacement therapy
Q. Match the following
Column IColumn IIA. Humulini. Possesses 21 amino acids.B. A-peptideii. Extra stretch present in pro-insulin.C. B-peptideiii. First genetically engineered hormone.D. C-peptideiv. Connects peptide chains.E. Disulphide Bondsv. Possesses 30 amino acids.
Column IColumn IIA. Humulini. Possesses 21 amino acids.B. A-peptideii. Extra stretch present in pro-insulin.C. B-peptideiii. First genetically engineered hormone.D. C-peptideiv. Connects peptide chains.E. Disulphide Bondsv. Possesses 30 amino acids.
- A-v, B-iv, C-iii, D-ii, E-i
- A- iii, B-i, C-v, D-ii, E-iv
- A-ii, B-iv, C-i, D-iii, E-v
- A-iv, B-iii, C-ii, D-i, E-v
Q. A correction or alleviation of a genetic disorder by the introduction of a normal gene copy into an affected individual is called
- gene probe
- gene duplication
- gene therapy
- gene cloning
Q. Name the hormone: (c) Maintains glucose level in the blood
Q. The first human hormone produced by recombinant DNA technology is:
- Insulin
- Estrogen
- Thyroxin
- Progesterone
Q. Name the four categories of materials for preparing vaccines...............
Q. The first human hormone produced by recombinant DNA technology is
- insulin
- thryoxin
- estrogen
- progesterone
Q. Edward Jenner is called father of
- Immunology
- Microbiology
- Virology
- Serology
Q. Edible vaccines is mainly produced by
- Micropropagation
- Protoplast fusion
- Transduction
- Molecular farming
Q. Make pairs using the indicators given as diseases and their vaccines.
Q. The first human hormone produced by recombinant DNA technology is:
- Estrogen
- Insulin
- Thyroxin
- Progesterone
Q. Maximum application of animal cell culture technology today is in the production of:
- Vaccines
- Edible proteins
- Interferons
- Insulin
Q. Which one of the following is a kinetin?
- Indole-3-pyruvic acid
- Acetyl GA3
- Ethyl Indoleacetate
- 6-Furfurylamino purine
Q.
Consult internet and find out how to make orally active protein pharmaceutical. What is the major problem to be encountered?