Blood Group

Q. What is DNA polymorphism? Why is it important to study it?

Q.

Can your blood type change as you get older?

Q. A normal visioned woman, whose father is colour blind, marries a normal visioned man. What would be the probability of her sons and daughters to be colour blind? Explain with the help of a pedigree chart.

Q. The example of ABO blood grouping also provides a good example of multiple alleles. Explain it .

Q. If a character is controlled by $5$ alleles of a gene, calculate the possible genotypes in population

1. $12$
2. $17$
3. $14$
4. $15$

Q.

Human urine is usually acidic because.

1. Sodium transporter exchanges one hydrogen ion for each sodium ion, in peritubular capillaries

2. Excreted plasma proteins are acidic

3. Potassium and sodium exchange generates acidity

4. Hydrogen ions are actively secreted into the filtrate

Q. A man of A blood group marries a woman of the AB blood group. Which type of progeny would indicate that man is heterozygous for blood group A?

1. AB
2. A
3. O
4. B

Q. Discuss briefly how a probe is used in molecular diagnostics.

Q.

Is A negative blood group rare?

Q. Occasionally, a single gene may express more than one effect. The phenomenon is called:

1. multiple allelism
   
2. pleiotropy
   
3. mosaicism
   
4. polygeny

Q.

Which of the following steps is taken to prevent the occurrence of erythroblastosis fetalis?

1. Blood transfusion in mother

2. Treating the mother with anti Rh antibodies

3. Aborting the second pregnancy

4. None of the above

Q. Which of the following blood group is called as universal donor?

1. O Rh-ve
2. O Rh+ve
3. AB Rh+ve
4. AB Rh-ve

Q. The antigens for Rh and ABO blood group are present on:

1. WBC
2. RBC
3. Platelet
4. Plasma

Q. Which one of the following statements is correct with regard to the principle of safe blood transfusion?

1. The donor’s RBCs should not contain antibodies against the recipient’s serum
2. The recipient’s serum should not contain the antibodies against the RBCs of the donor
3. The recipient’s serum should not contain antigens against the donor’s antibodies
4. The recipient’s RBCs should not contain antibodies against the donor’s antigen

Q. Children have A and B types of blood. What are the blood types of parents

1. A and O
2. AB and A
3. AB and O
4. A and B

Q. Even if a character shows multiple allelism, an individual will only have two alleles for the character. Why?

Q.

Husband and wife belong to blood group O and AB respectively. Given below are blood groups of different children. Which of those cannot be of the said couple?

1: Blood group A

2: Blood group B

3: Blood group O

4: Blood group AB

1. 1 & 2 only

2. 4 only

3. 2, 3 & 4 only.

4. 3 & 4 only

Q.

Clumping of RBC may occur when blood of one person is mixed with serum or blood of another person. This is due to:

1. antigen-antibody reaction

2. antitoxin-antibody reaction

3. antigen-antigen reaction

4. antibody-antibody reaction

Q.

What is so special about AB-positive blood?

Q. If red blood cells are placed in distilled water, they will

1. Shrink and collapse
2. First increase in volume and then burst
3. None of the above
4. Stick together

Q.

The blood groups of both the donor and the recipient should be known before transfusing.

Q.

Name the types of mutations.

Q. What would be the possible genotypes of children regarding ABO blood group if their mother is with blood group O and father with blood group AB?
[0.7 mark]

1. $I^A{I}^B\text{and}ii$
2. $I^{A}iand{I}^{B}i$
3. $I^A{I}^B,I^{A}iand{I}^{B}i$
4. $I^{A}i,I^{B}iandii$

Q. Erythroblastosis foetalis happens when mother is Rh ___ and the foetus is Rh ____.

1. –ve, +ve
2. –ve, –ve
3. +ve, –ve
4. +ve, +ve

Q. Name the scientist who introduced the ABO blood group.

1. Leeuwenhoek
2. Wiener
3. Landsteiner
4. Janssen

Q. In a certain population, the frequency of three genotypes is as follows:

Genotypes: BB Bb bb

Frequency: $22\%$ $62\%$ $16\%$

What is the likely frequency of B and b alleles?

Q.

State whether the following are true or false:

Mothers blood flows into the foetus through placenta.

1. True
2. False

Q. Read the following statements and choose the incorrect statement.

1. Active immunity is a slow immune response but pathogen specific
2. lgG and lgA imparts passive immunity to foetus
3. Anti-tetanus serum is an example of passive immunity
4. Active immunity is exemplified by a condition when a snake bites and host’s body naturally produces antibodies against snake venom

Q. The most popularly known blood grouping is ABO. It is named ABO and not ABC, because ‘O’ in it refers to

1. No antigens A and B on the surface of RBCs
2. Antigens A and B are present inside RBCs
3. Over dominance of antigen O on A and B
4. Only antigen B on the RBCs

Q. If the foetus is Rh (+) ve and the mother is Rh (-) ve, then

1. Foetus is attacked by antibodies of mother's blood
2. Foetus will transmit antibody to mother's blood
3. Foetus will transmit blood toxin to mother
4. Foetus is attacked by antigen of mother's blood