Cyclosporin

Q. Which of the following is wrongly matched in the given table:

1. $\begin{array}{cccc}& \text{Microbe}& \text{Product}& \text{Application}\\ \text{(A)}& \text{Tichoderma polysporum}& \text{Cyclosporin A}& \text{Immunosuppressive drug}\end{array}$
2. $\begin{array}{cccc}& \text{Microbe}& \text{Product}& \text{Application}\\ \text{(B)}& \text{Monascus purpureus}& \text{Statins}& \text{Lowering of blood cholesterol}\end{array}$
3. $\begin{array}{cccc}& \text{Microbe}& \text{Product}& \text{Application}\\ \text{(C)}& \text{Streptococcus}& \text{Streptokinase}& \text{Removal of clot from blood vessel}\end{array}$
4. $\begin{array}{cccc}& \text{Microbe}& \text{Product}& \text{Application}\\ \text{(D)}& \text{Clostridium butylicum}& \text{Lipase}& \text{Removal of oil stains}\end{array}$

Q.

Find out the name of the microbes from which Cyclosporin-A (an immunosuppressive drug) and statins (blood cholesterol lowering agents) are obtained.

Q. Cholesterol-lowering statins are produced by

1. fungi
2. bacteria
3. protozoan
4. blue green algae

Q. Assertion (A): A patient who has undergone organ transplantation, if not provided with cyclosporin A may reject the transplanted organ
Reason (R): Cyclosporin A inhibits activation of T cells and interferes with destruction of non-self cells

1. Both A and R are false
2. A is true but R is false
3. Both A and R are true and R is the correct explanation of A
4. Both A and R are true and R is not the correct explanation of A

Q.

What is Cyclosporin?

Q. The bioactive molecule used as an immunosuppressive agent during organ transplant is [1 mark]
(A) Tetracyclin
(B) Cyclosporin-A
(C) Statin
(D) Streptomycin

Q. Statins used for lowering blood-cholesterol level are extracted from

1. algae
2. bacteria
3. viruses
4. yeast

Q.

Cyclosporin A used as immunosuppressive agent is obtained from

1. Bacterium Bacillus subtilis

2. Fungus Trichoderma polysporum

3. both 1 and 2

4. Fungus Tolypocladiuminflatum

Q. Cyclosporin A, used as immune suppressive agent is obtained from

1. Bacillus subtilis
2. Plasmopara viticola
3. Trichoderma polysporum
4. Monascus purpureus

Q. Cyclosporin A, an immunosuppressive drug is produced by

1. Aspergillus niger
2. Monascus purpureus
3. Penicillium notatum
4. Trichoderma polysporum

Q. Cyclosporin A, used as an immunosuppressive agent in obtained from

1. Bacillus thuringiensis
2. Trichoderma polysporum
3. Tolypocladium inflatum
4. Saccharomyces cerevisiae

Q.

What is the meaning of phagocytosis?

Q.

Find out the name of the microbes from which Cyclosporin A (an immunosuppressive drug) and Statins (blood cholesterol lowering agents) are obtained.

Q. Mention the use of Cyclosporin A.

Q. Rejection of transplanted organ is prevented by regular use of

1. Cyclosporin
2. Calcitonin
3. Thrombin
4. Pyroxin
5. Aspirin

Q. Certain antibiotics have multiple physiological effects like decreasing blood cholesterol levels and acting as an immunosuppressant.

1. True
2. False

Q. Certain antibiotics have multiple physiological effects like decreasing blood cholesterol levels and acting as an immunosuppressant.

1. True
2. False

Q. Match the column I with column II

Column I	Column II
A. Colchicine	I. Immuno-suppresant drug
B. Cyclosporin A	II. Induced abortion
C. GABA	III. Mitotic poison
D. Mifepristone	IV. Inhibitory neurotransmitter

1. A- III, B- I, C- IV, D- II
2. A- III, B- II, C- I, D- IV
3. A- IV, B- III, C- I, D- II
4. A- IV, B- I, C- II, D- III

Q. _______A______ is a protein produced by the cells invaded by _____B_____.

The correct options are:

1. A - Interferons, B - bacteria
2. A - Interferons, B - virus
3. A - Serotonin, B - virus
4. A - Histamine, B - bacteria

Q. Drug for a medical treatment is obtained from organism.Find the correct option

1. Heart-Penicillium
2. Organ transplant-Trichoderma
3. Swine Flu-Monascus
4. AIDS-Pseudomonas

Q.

Cyclosporin A used as immunosuppressive agent is obtained from

1. Bacterium Bacillus subtilis

2. Fungus Trichoderma polysporum

3. Fungus Tolypocladiuminflatum

4. both 1 and 2