Formation of RBC

Q. Intrinsic factor that helps in the absorption of vitamin $B_{12}$ is secreted by:

1. Goblet cells
2. Hepatic cells
3. Oxyntic cells
4. Chief cells

Q.

What is erythropoiesis? Which hormone stimulates it?

Q. Increase in blood flow stimulates certain specific cells of cardiac atria to secrete:

1. ADH
2. Renin
3. Aldosterone
4. ANF

Q. Choose the correct sequence of enzyme activation in human kidney when there is a fall in GFR

1. Renin - Aldosterone - Angiotensin II
2. Renin - Angiotensin II - Aldosterone
3. Angiotensin II - Aldosterone - Renin
4. Aldosterone - Renin - Angiotensin II

Q. Which hormone stimulates the secretion of aldosterone from the adrenal cortex?

1. Renin
2. Vasopressin
3. ADH
4. Angiotensin II

Q. Hormone stimulating bone marrow to produce RBCs , ‘Erythropoietin’ is secreted by

1. Kidney
2. Adrenal cortex
3. Adrenal medulla
4. Delta cells of pancreas

Q.

The term haematuria is used to describe:

1. Internal bleeding

2. Blood poisoning

3. Blood cancer

4. Presence of red blood cells in urine

Q. Which of the following hormone helps to prevent the diuresis?

1. FSH
2. LH
3. MSH
4. ADH

Q. The hormone erythropoietin

1. Delays the maturation of RBC
2. Accelerates the production of RBC and Hb
3. Reduces the affinity of Hb towards $O_2$
4. Delays the production of protein heme

Q. Which leucocytes release histamine, serotonin and heparin?

1. Basophils
2. Neutrophils
3. Monocytes
4. Eosinophils

Q. Assertion :RBC production is regulated by kidneys. Reason: Erythropoietin hormone produced by kidneys reaches red bone marrow where it increases stem cells mitosis and speed up development of RBCs.

1. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
2. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
3. Assertion is correct but Reason is incorrect
4. Both Assertion and Reason are incorrect

Q. Abnormal increase in number of RBC in blood is

1. Leukemia
2. Sarcoma
3. Anaemia
4. Polycythemia

Q. 'Graveyard of RBCs' is

1. All of the above
2. Spleen
3. Kidney
4. Liver

Q. Stimulation of RBC production is by the hormone

1. Aldosterone
2. Adrenaline
3. Nor-Adrenaline
4. Erythropoietin

Q.

The ruptured RBCs are captured here and broken down by the phagocytic cells in the

1. 

2. 

3. 

4. 

Q. ............. and ............. pigments are formed by the decomposition of haemoglobin in the liver.

Q. Erythropoiesis begins in

1. red bone marrow
2. liver
3. both a and c
4. heart

Q. During sleeping, the rate of RBC formation

1. Increases
2. Decreases
3. Remains constant
4. None of the above

Q. A patient suffering from splenomegaly undergoes splenectomy. Which of the following processes will be affected?

1. RBC production will be stopped.
2. Removal of old RBC will be impaired.
3. Decreases in antibody production.
4. Generation of B cells will be stopped.

Q. Which of the following local hormone acts on G protein-coupled receptors?

1. Leukotriens
2. Erythropoietin
3. Gastrointestinal hormone
4. ANF

Q. Which one of the following human organs is often called as the "graveyard" of RBCs?

1. Kidney
2. Gallbladder
3. Liver
4. Spleen

Q. Haemoglobin contains

1. Fe${}^{++}$
2. Mg${}^{++}$
3. Na${}^{++}$
4. Ca${}^{++}$

Q. Assertion :Total count of RBC comes out to be very low in polycythemia. Reason: Number of erythrocytes get reduced in the condition of polycythemia.

1. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
2. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
3. Assertion is correct but Reason is incorrect
4. Both Assertion and Reason are incorrect

Q. Cells formed in the bone marrow are

Q. Which one of the following hormones controls the water and mineral metabolism?

1. Succus entericus
2. Insulin
3. Deoxycorticosterone
4. Progesterone

Q. Hb count of leukaemic female will be

1. 15 gm/dL
2. 8 gm/dL
3. > 16 gm/dL
4. 12-16 gm/dL

Q. People living at sea level have around 5 million RBC per cubic millimeter of their blood whereas those living at an altitude of 5400 metres have around 8 million. This is because at high altitude-

1. People get pollution-free air to breathe and more oxygen is available
2. There is more UV radiation which enhances RBC production
3. Atmospheric O${}_2$ level is less and hence more RBCs are needed to absorb the required amount of O${}_2$ to survive
4. People eat more nutritive food, therefore more RBCs are formed

Q. Which of the following are needed for blood clotting?

1. Ca${}^{++}$ and vitamin E
2. K${}^{+}$ and vitamin A
3. Ca${}^{++}$ and vitamin K
4. K${}^{+}$ and vitamin K

Q. Red blood cells

1. Divide amitotically
2. Do not divide
3. Divide by mitotic division
4. Divide by meiotic division