Inheritance of Autosomal Dominant Disorders

Q. Cystic fibrosis is an autosomal recessive disease. In a population of one hundred individuals, twenty-five are found to have the disease. Assuming Hardy - Weinberg equilibrium, what is the percent of the population that are carriers for cystic fibrosis?

1. 10%
2. 75%
3. 25%
4. 50%

Q.

Neurofibromatosis is a disease that affects both males and females. It causes nerve endings to form a tumorous growth that swells up in size. There is no affinity towards any sex. Also, if one of the parents has it, there is 50% chance that the offspring will suffer from it. What kind of disease is this?

1. Autosomal Dominant

2. X-Linked Recessive

3. X-Linked Dominant

4. Autosomal Recessive

Q.

What phenotype is associated with the genotype XXY?

Q. A diseased man marries a normal woman. The couple has 3 daughters and 5 sons. The daughters are diseased while the sons are normal. The gene of the disease is

1. Sex-linked dominant
2. Sex-linked recessive
3. Autosomal character
4. Sex-limited character

Q.

Regarding the assertion and reason; choose the correct option.

Assertion [A]: A genetic disease that affects only one parent can have 50% chance of affecting the child.

Reason [R]: An autosomal dominant defective allele can cause a disease even in heterozygous condition.

1. Assertion [A] is True and Reason [R] is True and is a correct explanation for [A].

2. Assertion [A] is True and Reason [R] is False.

3. Reason [R] is True and Assertion [A] is False.

4. Assertion [A] is True and Reason [R] is True but is an incorrect explanation to [A].

Q. If the father has autosomal dominant disease (heterozygous), then what will be the probability of having an affected offspring irrespective of sex of the child, if the mother is unaffected?

1. 90%
2. 10%
3. 50%
4. 100%

Q. A man and women, who do not show any apparent signs of a certain inherited disease have seven children (2 daughters and 5 sons). Three of the sons suffer from the given disease but none of the daughters are affected. Which of the following mode of inheritance do you suggest for this disease?

1. Sex-limited recessive
2. Sex-linked recessive
3. Sex-linked dominant
4. Autosomal dominant

Q. All the sons are hemophilic and daughters are normal of a haemophilic mother and normal father. What is this character called as?

1. Y linked recessive
2. X linked recessive
3. Y linked dominant
4. X linked dominant

Q.

Neurofibromatosis is a disease that affects both males and females. It causes nerve endings to form a tumorous growth that swells up in size. There is no affinity towards any sex. Also, if one of the parents has it, there is 50% chance that the offspring will suffer from it. What kind of disease is this?

1. Autosomal Dominant

2. X-Linked Recessive

3. Autosomal Recessive

4. X-Linked Dominant

Q.

Regarding the assertion and reason, choose the correct option.

Assertion [A]: A genetic disease that affects only one parent can have 50% chance of affecting the child.
Reason [R]: An autosomal dominant defective allele can cause a disease even in heterozygous condition.

1. Reason [R] is True and Assertion [A] is False.

2. Assertion [A] is True and Reason [R] is False.

3. Assertion [A] is True and Reason [R] is True and is a correct explanation for [A].

4. Assertion [A] is True and Reason [R] is True but is an incorrect explanation to [A].

Q.

Regarding the assertion and reason, choose the correct option.

Assertion [A]: A genetic disease that affects only one parent can have 50% chance of affecting the child.
Reason [R]: An autosomal dominant defective allele can cause a disease even in heterozygous condition.

1. Assertion [A] is True and Reason [R] is False.

2. Reason [R] is True and Assertion [A] is False.

3. Assertion [A] is True and Reason [R] is True and is a correct explanation for [A].

4. Assertion [A] is True and Reason [R] is True but is an incorrect explanation to [A].

Q.

Neurofibromatosis is a disease that affects both males and females. It causes nerve endings to form a tumorous growth that swells up in size. There is no affinity towards any sex. Also, if one of the parents has it, there is 50% chance that the offspring will suffer from it. What kind of disease is this?

1. Autosomal Dominant

2. X-Linked Recessive

3. Autosomal Recessive

4. X-Linked Dominant

Q.

Regarding the assertion and reason, choose the correct option.

Assertion [A]: A genetic disease that affects only one parent can have 50% chance of affecting the child.
Reason [R]: An autosomal dominant defective allele can cause a disease even in heterozygous condition.

1. Assertion [A] is True and Reason [R] is False.

2. Reason [R] is True and Assertion [A] is False.

3. Assertion [A] is True and Reason [R] is True and is a correct explanation for [A].

4. Assertion [A] is True and Reason [R] is True but is an incorrect explanation to [A].