Insulin and Its Mode of Action

Q.

Name a peptide hormone which acts mainly on hepatocytes, adipocytes and enhances cellular glucose uptake and utilization.

Q.

What are the metabolic effects of insulin?

Q. Statins produced by Monascus purpureus have been used as blood-cholesterol lowering agents.

How do statins lower the blood-cholesterol levels in the body?

1. They cause the breakdown of the cholesterol molecules
2. They eliminate chloesterol from the body
3. They inhibit the synthesis of cholesterol
4. They dissolve the cholesterol in the body

Q.
What is the Difference Differen type1 and type2 diabetes ???
which is more common?
Why?

Q.

How does insulin work in the body?

Q.

Chemically insulin is a

1. Lipid

2. Steroid

3. Carbohydrate

4. Protein

Q.

The hormone that helps in the conversion of glucose to glycogen is

1. Adrenaline

2. Insulin

3. Oxytocin

4. Glucagon

Q. Explain with reasons:
(e) Vasopressin and insulin (Deficiency disorder).

Q. Match the following from column 1 and column 2

Column 1 (Hormone)	Column 2 (Effect)
p. Parathyroid hormone	1. Hypocalcemic
q. Glucagon	2. Hypoglycemic
r. Insulin	3. Hypercalcemic
s. Calcitonin	4. Hyperglycemic

1. p-1, q-2, r-3, s-4
2. p-3, q- 4, r-2, s-1
3. p-4, q-2, r-1, s-3
4. p-2, q- 3, r- 4, s-1

Q.

Question 23.4

State whether true or false

Insulin resistance results in a disease called diabetes mellitus.

Q. Which of the following is a precursor of vitamins and steroid hormones

1. Lipids
2. Cholesterol
3. Lipoic acid
4. None of the above

Q. A person with diabetes mellitus is likely to have a deficiency or poor response to insulin. Elevation of blood glucose levels will typically lead to a concordant rise in insulin. However, in some of these patients, insulin is ineffective in its ability to regulate blood sugar levels.
What is the unresponsive mechanism?

1. Negative control
2. Negative feedback
3. Positive feedback
4. Positive control

Q.

Name a disease caused by a broken feedback loop?

Q. Name the hormone that regulates the raise in blood sugar and mention the source of it.

Q. Which hormones stimulates the production of pancreatic juice and bicarbonate?

1. Insulin and glucagon
2. Angiotensin and epinephrine
3. Gastrin and insulin
4. Cholecystokinin and secretin

Q.

The hormone that helps in the conversion of glucose to glycogen is

1. Adrenaline

2. Insulin

3. Oxytocin

4. Glucagon

Q. Insulin is a

1. vitamin
2. lipid
3. hormone
4. enzyme

Q. Which hormone stimulates the production of RBC and also decreases the WBC count in blood?
(1) Erythropoietin
(2) Cortisol
(3) Growth hormone
(4) Thyroxine

Q. Name a peptide hormone which acts mainly on hepatocytes, adipocytes and enhances cellular glucose uptake and utilization.

1. Gastrin
2. Insulin
3. Secretin
4. Glucagon

Q.

Diabetes can be caused due to

1. Destruction of α cells in islets of Langerhans

2. Destruction of β cells in islets of Langerhans

3. Destruction of Δ cells in islets of Langerhans

4. Destruction of γ cells in islets of Langerhans

Q. Which one of the following hormone has potential to prevent certain chronic disease like cancer and multiple sclerosis?

1. Dehydro-epiandro sterone
2. Melatonin
3. Testosterone
4. Estrogen

Q. Vitamin A is produced from carotene in

1. Blood
2. Skin
3. Intestinal tract
4. Liver

Q. What happens when beta cells of the pancreas release insulin into the blood?

1. Alpha cells are stimulated to release glucose into the blood.
   
2. The liver breaks down glycogen to glucose.
3. Blood glucose levels rise to a set point and stimulate glucagon release.
4. Body cells take up more glucose.

Q. Which of the following hormones are derived from tyrosine?

1. Epinephrine, Thyroxine
2. Insulin, Parathormone
3. Vasopressin, Oxytocin
4. Thyroxine, Parathormone

Q. name d disease caused due to insufficient insulin

Q. Ca${}^{2+}$ level is controlled by

1. Adrenal cortex
2. Hypothalamus
3. Pituitary
4. Thyroid and parathyroids

Q. What happens when beta cells of the pancreas release insulin into the blood?

1. Blood glucose levels rise to a set point and stimulate glucagon release.
2. Body cells take up more glucose.
3. The liver breaks down glycogen to glucose.
4. Alpha cells are stimulated to release glucose into the blood.
   

Q. Insulin is a

1. vitamin
2. enzyme
3. lipid
4. hormone

Q.

Diabetes can be caused due to

1. Destruction of α cells in islets of Langerhans

2. Destruction of β cells in islets of Langerhans

3. Destruction of Δ cells in islets of Langerhans

4. Destruction of γ cells in islets of Langerhans