Amines as Nucleophiles

Q. What is the $IUPAC$ name of the organic compound formed in the following chemical reaction ?

1. $\text{2-methylbutan-2-ol}$
2. $\text{pentan-3-ol}$
3. $\text{pentan-2-ol}$
4. $\text{2- methylpropan-2-ol}$

Q.

Why is it essential to wash the precipitate with water before estimating it quantitatively?

Q.

When aniline is treated with acetyl chloride in presence of anhydrous aluminium chloride, the main product is

1. $\rho$ -aminoacetophenone

2. m-aminoacetophenone

3. o- aminoacetophenone

4. both (a) and (b)

Q. The amine that does not react with acetyl chloride is :

1. $C{H}_{3}N{H}_2$
2. $Allofthese$
3. $(C{H}_3{)}_{2}NH$
4. $(C{H}_3{)}_{3}N$

Q. Which of the following compounds does not undergo Friedel-Crafts reaction neither alkylation nor acylation ?

1. Benzene
2. Aniline
3. Cholorobenzene
4. Benzaldehyde

Q. Which of the following reagents help in conversion of $C{H}_{3}CH=C{H}_2\to C{H}_{3}C{H}_{2}C{H}_{2}OH$ ?

1. $Na$/ether
2. $HBr$/Peroxide followed by aq. $KOH/\Delta$
3. Acidic $KMn{O}_4$
4. None of these

Q. Which of the following reaction is/are correct?

1. 
2. 
3. 
4. all of these

Q. Which of the following reactions does not give benzaldehyde?

1. Rosenmund reaction
2. Etard reaction
3. Gatterman-Koch reaction
4. Friedel craft acylation reaction

Q. An organic compound $‘A^{\prime }\left(C_3{H}_{9}N\right)$ reacts with benzene-sulphonyl chloride to give a solid insoluble in alkali. The structure of $‘A^{\prime }$ is :

1. $C{H}_{3}NH{C}_2{H}_5$
2. Insufficient data to predict
3. $(C{H}_3{)}_{3}N$
4. $C{H}_{3}C{H}_{2}C{H}_{2}N{H}_2$

Q. A nucleophilic substitution reaction can occur via $S_{N}1$ and $S_{N}2$ mechanism. The ease of the reaction to go through $S_{N}1$ or $S_{N}2$ depends upon many factors. Ionisation has an important role to play in such reaction. The process of ionisation initially generates a carbocation and a counter ion in proximity to each other. This species is called an initimate-ion pair. This species can proceed to a solvent seperated ion pair, in which one or more solvent molecules have inserted between the carbocation and the leaving group. Then diffusion of ions occurs.
What would be the expected stereochemistry of the product if a coming nucleophile attacks on carbocation at intimate-ion pair stage.

1. Inversion
2. Racemisation
3. Retention
4. No reaction will occur at intimate-ion pair stage

Q. Secondary amine can be produced by reduction of:

1. nitrobenzene
2. methyl cyanide
3. methyl isocyanide
4. nitroethane

Q. The maximum number of compounds with the molecular formula $C_4{H}_{11}N$, which give an alkali soluble compound when reacted with benzenesulfonyl chloride is:

Q. The named reaction used to synthesise amides from amines and acid chlorides is called:

1. Perkin's reaction
2. Acetylation reaction
3. Schotten-Baumann reaction
4. Friedel-Crafts reaction

Q. Wolf Kishner reduction reduces:

1. $-CHO$ group
2. Both B and C
3. $RCOR$ group
4. $-COOH$ group

Q. Relative basic strength of following compounds is

1. IV > II > III > I
2. III > I > IV > II
3. I > III > II > IV
4. II > IV > I > III

Q. In the following reactions, the product S is

1. 
2. 
3. 
4. 

Q. For the given reaction, which of the following compounds is the best nucleophile?

1. Only II
2. I and II
3. Only I
4. I, III

Q. $A\stackrel{aq.KOH}{\leftarrow }{C}_2{H}_{5}Br\stackrel{ale.KOH}{\to }B$
The correct statement is

1. 'A' is obtained by substitution reaction
2. 'B' is obtained by elimination reaction
3. 'A' is the isomer of dimethyl ether while 'B' is the dehydrated compound of 'A'
4. All of these

Q. For the given reaction, which of the following compounds is the best nucleophile?

1. I, III
2. Only II
3. I and II
4. Only I

Q.

What does alkyl mean?

Q. Which of the following combination of reagents can bring the shown transformation ?

1. $C{H}_{3}ONa,Mg/\text{ether},C{O}_2,H_{2}O/H^{+}$
2. $C{H}_{3}ONa,KCN/DMSO,H_{2}O/H_{2}S{O}_4,\text{heat}$
   
3. $Mg/\text{ether,}C{O}_2,H_{2}O/H^{+},C{H}_{3}ONa$
4. $NaOH,Mg/\text{ether,}C{O}_2,H_{2}O/H^{+},C{H}_{3}I$

Q. (a) Write the product when D-glucose reacts with conc. $HN{O}_3$.

(b) Amino acids show amphoteric behaviour. Why?

(c) Write one difference between $\alpha$-helix and $\beta$-pleated structures of proteins.

Q. The maximum number of compounds with the molecular formula $C_4{H}_{11}N$, which give an alkali soluble compound when reacted with benzenesulfonyl chloride is:

Q.

KCl is known as

1. Sylvine

2. Bauxite

3. Calamine

4. Rutile

Q.

Which of the following is used as antioxidant in rubber industry

1. Acetaldehyde ammonia

2. Schiff base

3. Schiff's reagent

4. Benzene diazonium chloride

Q. What is the correct structure of the amine produced by the Hoffmann degradation of benzamide ?

1. 
2. 
3. 
4. 

Q. 29. Give the mechanism for formation of diazoniumsalt when bemzene reacts with NaNO2 and HCl

Q. Which of the following does not undergo benzoin condensation?

1. 
2. 
3. 
4. 

Q. Aniline reacts with acetaldehyde to form

1. Schiff's base
2. Carbylamine
3. Immine
4. None of these

Q. In the reaction: $Ph-CH=CH-C{H}_{2}Br\stackrel{HOH}{\to }\left[X\right]$

$\left[X\right]$ would be:

1. $Ph-CH=CH-C{H}_{2}OH$
2. $Ph-\stackrel{OH}{\stackrel{|}{C}}H-CH=C{H}_2$
3. $Ph-C{H}_2-CH=C{H}_2$
4. Both (a) and (b)