Receptors as Drug Targets

Q. Drugs which bind the receptor site and inhibit its natural function are called

1. neurotransmitters
2. chemical messengers
3. agonists
4. antagonists

Q.

Drugs that mimic the natural messenger by switching on the receptor are called:

1. Messenger

2. Agonists

3. Inhibitor

4. Antagonists

Q.

Assertion and Reason
In the following questions a statement of assertion (A) followed by a statement reason (R) is given. Choose the correct answer out of the following choice..
(a) Assertion and reason both are correct statements but reason does not explain assertion.
(b) Assertion and reason both are correct and reason explains asssWon.
(c) Both assertion and reason are Wrong statements.
(d) Assertion is correct statement reason is wrong statement.
(e) Assertion is wrong statement reason is correct statement.

Assertion (A) Receptors are crucial to body's communication process.
Reason (R) Receptors are proteins.

Q.

What is the chemical nature of the receptor?

Q. Which of the following is a neurotransmitter?

1. Dopamine
2. Serotonin
3. Adrenaline
4. All of these

Q.

The most useful classification of drugs for medicinal chemists is ........
(a) on the basis of chemical structure
(b) on the basis of drug action
(c) on the basis of molecular targets
(d) on the basis of the pharmacological effect

Q.

In the body, message between two neurons and that between neurons to muscles is communicated through certain chemicals. These chemicals are the:

1. Chemical messengers

2. Cell membrane

3. Binding site

4. Receptor

Q. Which of the following is not a classification of drugs?

1. Based on size
2. Based on chemical structure
3. Based on drug action
4. Based on molecular targets

Q.

Match the class of compounds given in Column I with their functions given in Column II
$\begin{array}{cc}\text{Column I}& \text{Colum II}\\ \text{A. Antagonists}& \text{1. Communicate message between two neurons}\\ & \text{and that between neuros to muscles}.\\ \text{B. Agonists}& \text{2. Bind to the receptor site and inhibit its}\\ & \text{natural function.}\\ \text{C. Chemical messenger}& \text{3. Crucial to body's communication process.}\\ \text{D. Inhibitors}& \text{4. Mimic the natural messenger.}\\ \text{E. Receptors}& \text{5. Inhibit activites enzymes.}\end{array}$

Q.

How are receptor proteins located in the cell membrane?

Q. Identify the compound which does not act as a target for drug action in the human body?

1. RNA
2. DNA
3. Vitamin C
4. Protein

Q. The compound(s) which act as a target for drug action in the human body is/are:

1. RNA
2. DNA
3. Vitamin C
4. Protein

Q. Where are receptors located?

Q.

Do proteins bind to receptors?

Q. Drugs which bind the receptor site and inhibit its natural function are called

1. chemical messengers
2. agonists
3. antagonists
4. neurotransmitters

Q.

Where are receptors located?

Q.

Drugs like aspirin can be classified on the basis of:

1. Drug action

2. Pharmacological effect

3. Molecular target

4. Chemical structure

Q. Assertion : Receptor proteins show selectivity for one chemical messenger over the other
Reason : Chemical messenger binds to the receptor site and inhibits is natural function

1. Assertion is correct but Reason is incorrect
2. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
3. Both Assertion and Reason are incorrect
4. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
5. Assertion is incorrect but Reason is correct
6. Answer required

Q. Drugs that bind to the receptor sites and inhibit its natural function are called analgesics.

1. True
2. False

Q. Explain allosteric inhibition with an example.

Q.

Assertion and Reason
In the following questions a statement of assertion (A) followed by a statement reason (R) is given. Choose the correct answer out of the following choice..
(a) Assertion and reason both are correct statements but reason does not explain assertion.
(b) Assertion and reason both are correct and reason explains asssWon.
(c) Both assertion and reason are Wrong statements.
(d) Assertion is correct statement reason is wrong statement.
(e) Assertion is wrong statement reason is correct statement.

Assertion (A) Chemical messengers are chemicals that enable communication of message between two neurons or between neurons and muscles.
Reason (R) Chemicals enter the cell through receptor.

Q.

Assertion and Reason
In the following questions a statement of assertion (A) followed by a statement reason (R) is given. Choose the correct answer out of the following choice..
(a) Assertion and reason both are correct statements but reason does not explain assertion.
(b) Assertion and reason both are correct and reason explains asssWon.
(c) Both assertion and reason are Wrong statements.
(d) Assertion is correct statement reason is wrong statement.
(e) Assertion is wrong statement reason is correct statement.

Assertion (A) Receptor proteins show selectivity for one chemical messenger over the other.
Reason (R) Chemical messenger binds to the receptor site and inhibits its natural function.

Q. Which of the following is a neurotransmitter?

1. Dopamine
2. Serotonin
3. Adrenaline
4. All of these

Q. What is the source of receptor proteins?

1. Interior of a cell
2. Fixed in the cell membrane partially inside and partially projected outward
3. Cell wall
4. Out of cell wall

Q. Assertion :Chemical messengers are received at the binding sites of receptor proteins. Reason: Chemical messengers gives messages to the cell without entering the cell.

1. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
2. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
3. Assertion is correct but Reason is incorrect
4. Both Assertion and Reason are incorrect

Q. Which of the following increases blood pressure and heart beat?

1. Dopamine
2. Noradrenaline
3. Serotonin
4. Adrenaline

Q.

1. True
2. False
3. Ambiguous
4. None of these

Q. Assertion : Chemical messengers are chemicals that enable communication of message between two neurons or between neurons and muscles.
Reason : Chemicals enter the cell through receptor.

1. Both Assertion and Reason are incorrect.
2. Both Assertion and Reason are correct and Reason is the incorrect explanation for Assertion.
3. Both Assertion and Reason are correct.
4. Assertion is correct but Reason is incorrect.
5. non of these
6. A and B

Q.

Assertion and Reason
In the following questions a statement of assertion (A) followed by a statement reason (R) is given. Choose the correct answer out of the following choice..
(a) Assertion and reason both are correct statements but reason does not explain assertion.
(b) Assertion and reason both are correct and reason explains asssWon.
(c) Both assertion and reason are Wrong statements.
(d) Assertion is correct statement reason is wrong statement.
(e) Assertion is wrong statement reason is correct statement.

Assertion (A) Chemicat messenger gives message to the cell without entering the cell.
Reason (R) Chemical messenger is received at the binding site of receptor proteins.

Q. Identify the compound which does not act as a target for drug action in the human body?

1. RNA
2. DNA
3. Vitamin C
4. Protein