Central Dogma

Q.

What is recombination virus?

Q.

What part of central dogma is not always followed in viruses?

Q. Which of the following is not a feature of eukaryotic gene expression?

1. Polycistronic mRNA are mostly not found
2. Many genes are interrupted by noncoding DNA sequences
3. RNA synthesis and protein synthesis are coupled
4. mRNA is often extensively modified before translation

Q.

Which vector is used in gene therapy?

Q. Protein is a polypeptide of amino acids.

1. True
2. False

Q.

This section contains 1 Matrix Match type question, which has 2 Columns (Column I and Column II). Column I has four entries (A), (B), (C) and (D), Column II has four entries (P), (Q), (R) and (S). Match the entries in Column I with the entries in Column II. Each entry in Column I may match with one or more entries in Column II.इस खण्ड में 1 मैट्रिक्स मिलान प्रकार का प्रश्न है, जिसमें 2 कॉलम (कॉलम I तथा कॉलम II) हैं। कॉलम I में चार प्रविष्टियाँ (A), (B), (C) तथा (D) हैं, कॉलम II में चार प्रविष्टियाँ (P), (Q), (R) तथा (S) हैं। कॉलम I में दी गयी प्रविष्टियों का मिलान कॉलम II में दी गयी प्रविष्टियों के साथ कीजिए। कॉलम I में दी गयी प्रत्येक प्रविष्टि का मिलान कॉलम II में दी गयी एक या अधिक प्रविष्टियों के साथ हो सकता है।

Match the Columns and choose the appropriate answer

कॉलमों का मिलान करें और सही उत्तर चुनें

Match the following Columns.

निम्नलिखित कॉलमों का मिलान कीजिए।

	Column (कॉलम)-I		Column (कॉलम)-II
(A)	28S rRNA	(P)	Synthesized by RNA polymerase III आरएनए (RNA) पॉलिमरेज III द्वारा संश्लेषित होता है
(B)	5S rRNA	(Q)	Enhance peptide bond formation in prokaryotes प्रोकैरियोट्स में पेप्टाइड बंध के निर्माण को बढ़ाता है
(C)	tRNA	(R)	Synthesized by RNA polymerase I आरएनए (RNA) पॉलिमरेज I द्वारा संश्लेषित होता है
(D)	23S rRNA	(S)	Structural RNA संरचनात्मक आरएनए (RNA) है

1. A-RS, B-PS, C-P, D-QS
2. A-R, B-P, C-P, D-QS
3. A-PRS, B-PQS, C-P, D-QS
4. A-PQRS, B-PRS, C-PQ, D-QS

Q. Which of the following summarises the cental dogma of molecular biology in humans?

1. DNA transcribed to proteins and proteins translated into RNA.
2. RNA transcribed to DNA and DNA translated into proteins.
3. DNA transcribed to RNA and RNA translated into proteins.
4. Protein transcribed to DNA and translated into RNA

Q. Select the options which will result in expression of a human gene into functional proteins.
I. cDNA for the protein is inserted into the genome of an E. coli host.
II. mRNA is inserted into the genome of an E. coli host.
III. Gene is inserted into the genome of Saccharomyces.
IV. Gene is inserted into the genome of E. coli host.

1. I and II
2. II and III
3. I and III
4. Only III

Q. Central dogma of genetic information was modified by the discovery of

1. Reverse transcriptase
2. DNA polymerase
3. RNA polymerase
4. Ligase

Q. In a eukaryotic cell, tanscription occurs in the , and translation occurs in the .

1. nucleus
2. mitochondria
3. chloroplast
4. cytoplasm