Competitive Inhibition

Q. Which of the following is true for competitive enzyme inhibition?

1. Decrease in $V_{max}$ and $K_m$
2. Unchanged $V_{max}$ and decrease in $K_m$
3. Unchanged $V_{max}$ and increase in $K_m$
4. Increase in $V_{max}$ and $K_m$

Q. Which of the following is true for competitive inhibition?

1. $K_m$ decreases but $V_{max}$ increases
2. $K_m$ increases but $V_{max}$ decreases
3. $K_m$ increases but $V_{max}$ remains the same
4. $K_m$ decreases but $V_{max}$ remains the same

Q.

Find the incorrect statement/s regarding the factors affecting enzymatic activity or its inhibition
I. Product formed during a reaction can inhibit enzyme activity.
II. Competitive factors or replacement enzymes can act as inhibitors.
III. Change in the active site, can inhibit the action of enzymes.
IV. Increase in temperature (upto a limit), generally increases the rate of enzymatic activity.

1. I only

2. II only

3. $ll\&lll$

4. IV only

5. None of these

Q.

Find the incorrect statement/s regarding the factors affecting enzymatic activity or its inhibition
I. Product formed during a reaction can inhibit enzyme activity.
II. Competitive factors or replacement enzymes can act as inhibitors.
III. Change in the active site, can inhibit the action of enzymes.
IV. Increase in temperature (upto a limit), generally increases the rate of enzymatic activity.

1. I only

2. II only

3. $ll\&lll$

4. IV only

5. None of these

Q. The given graph shows the effect of substrate concentration on the rate of reaction of the enzyme green-gram-phosphatase. What does the graph indicate?

1. The rate of the enzyme reaction is directly proportional to the substrate concentration
2. Presence of an enzyme inhibitor in the reaction mixture
3. Formation of an enzyme-substrate complex
4. At higher substrate concentration the pH increases