Gene Therapy

Q.

The genetic defect - Adenosine Deaminase (ADA) deficiency may be cured permanently by

1. periodic infusion of genetically engineered lymphocytes having functional ADA C-DNA

2. administering adenosine deaminase activators

3. introducing bone marrow cells producing ADA into cells at early embryonic stages

4. enzyme replacement therapy

Q. ELISA can give a false test in the beginning of an infection due to

1. Low antibody
2. Denatured pathogen
3. Low concentration of pathogen
4. Antibody may not bind tightly to the titer plate

Q. In gene therapy, a functional gene is inserted into:

1. An individual only
2. An embryo only
3. Either an individual or an embryo
4. Both an individual and an embryo

Q. The most popular vector used in human gene therapy is

1. Plasmid
2. Phage
3. PUC 18
4. Retrovirus

Q. Bt protein is made as an inactive protein.

1. True
2. False

Q. Why is gene therapy needed?

1. Certain viral diseases need to be combated by gene silencing
2. Genetic disorders cannot be cured by drug based medicines
3. Gene therapy is a better cure for diseases as it has no side effects
4. Gene therapy can be designed to suit your genome and hence is more effective