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Question

A 36 year old woman is training for her first marathon, and her coach has her keeping a pace that allows her to stay below her anaerobic threshold. By avoiding anaerobic muscle glycolysis, the pyruvate produced in the muscle does not accumulate because it is converted to which one of the following?

A
Ethanol
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B
Lactic acid
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C
Acetyl CoA
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D
OAA
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Solution

The correct option is C Acetyl CoA
During aerobic conditions, when oxygen is not limiting, the pyruvate is converted to acetyl CoA to generate energy via the TCA cycle and oxidative phosphorylation.
During anaerobic conditions, generated by heavy strenuous exercise, pyruvate is convereted in lactate in muscles or ethanol in yeast cells.

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