Number of molecules in a chain = 12
Number of molecules with initials A = 3
Number of molecules with initials C = 3
Number of molecules with initials G = 3
Number of molecules with initials T = 3
Thus, total arrangements of all the molecules in the chain = Number of arrangements of 12 things of which 3 are similar to the first kind, 3 are similar to the second kind, 3 are similar to the third kind and 3 are similar to the fourth kind
= = 369600