The correct option is C SAN
A specialised cardiac neuro-musculature called the nodal tissue is distributed throughout the heart. Sino-atrial node (SAN) is a patch of this tissue which is found at the upper right corner of the right atrium of the heart. This is able to generate action potentials without the help of any external stimuli. Hence, it is autoexcitable in nature. Since, the rhythmic contractile activity of the heart is initiated by the SAN, it is also called as the natural pacemaker of the heart. It is responsible for generating the number of action potentials in the heart. If SAN fails to function, then, the normal contractile activity of the heart will get disrupted. Hence, an artificial pacemaker has to be grafted in such a patient at the site of SAN.