A disease caused due to mutation in DNA resulting in the production of sickle shaped RBCs.

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Solution

Effects of mutation are sickle anemia. Sickle anemia is a genetic disease with severe symptoms, including pain and anemia. The disease is caused by a mutated version of the gene that helps make hemoglobin.

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Similar questions

Statement 1: A blood disease caused by gene mutation is sickle cell anaemia.

Statement 2: It results in the production of sickle-shaped WBCs

Q. Sickle cell anaemia results due to mutation caused by

Q. Two Mark Questions :
A relevant portion of

β

-chain of haemoglobin of a normal human is
Val-His-Leu-Thr-Pro-Glu-Glu
1 2 3 4 5 6 7
The codon for the sixth amino acid is GAG. It mutates to GAA due to mutation 'A' and GUG due to mutation 'B'. Haemoglobin structure did not change as a result of mutation 'A' but mutation 'B' led to sickle cell-shaped RBCs. Explain giving reasons how could mutation 'B' change the haemoglobin structure and not mutation 'A'.

Q. Statement 1: Genetic disorder caused by change in the molecular structure of haemoglobin is sickle cell anaemia.

Statement 2: It results in the production of sickle-shaped WBC.

In a population of individuals living in a forest, few individuals developed sickle shaped RBCs in their blood.During a severe malarial attack these individuals with sickle shaped RBCs survived and were not infected with the disease. This can be an example for …………………… which has given that small group ……………………….. over others.

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