The correct options are
A Disturbed body structure or function
B Discomfort
C A cause for showing symptoms
D Unhealthy state
A disease means 'disturbed ease'. It shows disturbance, discomfort and symptoms in an organism. It could be due to disturbed structure or function of the body and this disturbance may be because of internal or external reasons. A disease can also be defined as an unhealthy state where something bad happens to body or mind.