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Question

(a) Expand VNTR and describe its role in DNA fingerprinting.
(b) List any two applications of DNA fingerprinting technique.

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Solution

a) VNTR is an abbreviated form for Variable Number Tandem Repeats.
It is the location of a nucleotide sequence in a genome arranged as tandem repeat. It belongs to a class of satellite DNA. The number of copies of nucleotide differs from chromosome to chromosome in an individual. Each variant acts as an inherited allele, allowing them to be used for personal or parental identification. Their analysis is useful in genetics and biological research, forensics, and DNA fingerprinting. In DNA fingerprinting, the number of tandem repeats and its size is taken into count.
b) DNA fingerprinting is used to find criminals by forensic department. It is also used to solve paternity disputes. It is also used to find inherited diseases in newborn and prenatal babies.



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