Question

A fall in glomerular filtration rate activates

• A. adrenal medulla to release adrenaline
• B. juxtaglomerular cells to release renin
• C. posterior pituitary to release vasopressin
• D. adrenal cortex to release aldosterone

Answer 1

The correct option is B juxtaglomerular cells to release renin

The kidneys have in-built mechanism for the regulation of glomerular filtration rate. One such efficient mechanism is carried out the juxtaglomerular apparatus (JGA). JGA is a special sensitive region formed by the cellular modifications at the location of contact of distal convoluted tubule and the afferent arteriole. A fall in GFR can activate the JG cells to release renin. This can stimulate the glomerular blood flow and thereby the GFR comes back to normal.