4
Question
A functional ADA cDNA is introduced into the patient’s lymphocytes using _______ vector.
A functional ADA cDNA is introduced into the patient’s lymphocytes using _______ vector.
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Solution
The correct option is B retroviral
Retroviruses are the most widely used viral vectors in gene therapy as they have the ability to transfer their single stranded RNA genome into double stranded DNA with the help of reverse transcriptase.
Retrovirus is considered as a vector for precise transmission of the transgene into the host cell progeny by integrating their complementary DNA into the host genome during their life cycle. Retroviruses enter mammalian cells via specific cell surface receptors, which limit their range of infections.
Retroviruses are the most widely used viral vectors in gene therapy as they have the ability to transfer their single stranded RNA genome into double stranded DNA with the help of reverse transcriptase.
Retrovirus is considered as a vector for precise transmission of the transgene into the host cell progeny by integrating their complementary DNA into the host genome during their life cycle. Retroviruses enter mammalian cells via specific cell surface receptors, which limit their range of infections.
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