Question

a functional ADAcDNA can be introduced into cells of the patients receiving gene therapy by using vector constituted by

• A. E.coil
• B. Reoviridae
• C. Retrovirus
• D. Agrobacterium

Answer 1

The correct option is A E.coil

The deficiency of the purine salvage enzyme adenosine deaminase is associated with severe B and T-cell dysfunction. In order to investigate the ADA molecule, gene therapy using E.coli, cDNA clones encoding ADA gene sequences are obtained.

So the correct option is 'E.coli'.