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Question

A laboratory blood test is 99% effective in detecting a certain disease when patient is infected actually by the disease. However, the test also yields a false positive result for 0.5% of the healthy person tested if 0.1 percent of the population actually has the disease, what is the probability that a person has the disease given that his test result is positive?

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Solution

Let
A: Person has the disease
B: Person does not have the disease
C: Test result is positive

P(A|C)=P(A).P(C|A)P(B).P(C|B)+P(A).P(C|A)

P(A)= Probability that person has disease =0.1%=0.1100=0.001
P(C|A)= Probability that test result is positive, if the person has the disease =99%=99100=0.99
P(B)= Probability that person does not have the disease =99.9%=99.9100=0.999
P(C|B)= Probability that test result is positive, if the person does not have the disease =0.005

P(A|C)=0.001×0.990.999×0.005+0.001×0.99
=99×105105(499.5+99)
=99598.5
=9905985
=22133
Therefore, required probability is 22133.

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