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Question

A male human is heterozygous for autosomal genes A and B and is also hemizygous for haemophilic gene h. What proportion of his sperms will be abh ?

A
1/8
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B
1/32
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C
1/16
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D
1/4
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Solution

The correct option is A 1/8
When a human male is heterozygous for autosomal gene A and B and also a hemizygous for haemophilic gene h then his genotype will be AaBbX h Y as haemophilia is a X-linked recessive disorder. The gametes produced from this genotype will be abX h , abY, ABX h , ABY, AbX h , AbY,aBX h, and aBY. So, the total number of sperm carries abh is 1 out of 8 gametes i.e., 1/8 or 12.5%. Thus, the correct answer is option A.

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