Question

A man with extra X-chromosome suffers from

• A. Down's syndrome
• B. Klinefelter's syndrome
• C. Bleeder's syndrome
• D. Turner's syndrome

Answer 1

Answer: (B)

Klinefelter's syndrome

Klinefelter syndrome is a sex chromosome disorder in boys and men that results from the presence of an extra X chromosome in cells. People typically have 46 chromosomes in each cell, two of which are the sex chromosomes. Females have two X chromosomes (46,XX), and males have one X and one Y chromosome (46,XY). Most often, boys and men with Klinefelter syndrome have the usual X and Y chromosomes, plus one extra X chromosome, for a total of 47 chromosomes (47,XXY). Boys and men with Klinefelter syndrome have an extra copy of multiple genes on the X chromosome. The activity of these extra genes affects many aspects of development, including sexual development before birth and at puberty.

So, the correct answer is 'Klinefelter's syndrome'.