A minimum changes in potential difference which is sufficiently significant for the generation of action potential is

EPSP

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Threshold stimulus

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IPSP

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Peak potential

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Solution

The correct option is C Threshold stimulus
The threshold stimulus can be defined as the minimum amount of change in the potential difference which is significant of the generation of an action potential. Below this, no action potential can be generated.
So, the correct answer is 'Threshold stimulus'.

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