Question

A patient was administered a chemical agent called Guanfacine hydrochloride after the patient showed the symptoms like shortness of breath and headache. Guantacme hydrochloride is a known stimulant of central $\alpha -2$ -adrenergic receptors of the medulla regulating the sympathetic nervous system. The patient in this case must be suffering from

• A. Hypertension
• B. Hyperslimulation
• C. Hyperpolarization
• D. None of the above

Answer 1

The correct option is A Hypertension

Alpha 2 receptors in the brain stem and in the periphery inhibit sympathetic activity and thus lower blood pressure.

Guanfacine is an antihypertensive drug whose principal mechanism of action is the stimulation of central α2-adrenergic receptors. By stimulating these receptors, guanfacine reduces sympathetic nerve impulses from the vasomotor center to the heart and blood vessels. This decreases blood pressure.

So, the correct option is 'Hypertension'.