Question

A patient who has an organ transplant was given cyclosporine-A. Mention the microbial source and state the reason for administration of this bioactive molecule.

Answer 1

Cyclosporin A is produced from fungi Trichoderma polysporum. Cyclosporin A has Cyclosporine injection is given together with a steroid medicine to prevent the body from rejecting a transplanted organ (e.g., kidney, liver, or heart). Cyclosporine works by suppressing the immune system to prevent the white blood cells from trying to get rid of the transplanted organ.