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Question

A person suffering from a disease caused by Plasmodium, experiences recurring chill and fever at the time when

A
The microgametocytes and megagametocytes are being destroyed by the WBCs.
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B
The sporozoites released from RBCs are being rapidly killed and broken down inside spleen.
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C
The trophozoites reach maximum growth and give out certain toxins.
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D
The parasite after its rapid multiplicaiton inside RBCs ruptures them, releasing the stage to enter fresh RBCs.
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Solution

The correct option is D The parasite after its rapid multiplicaiton inside RBCs ruptures them, releasing the stage to enter fresh RBCs.
The malarial paroxysm usually last 4-8 hours and begins with a sudden onset of chills in which the patient experiences an intense feeling of cold and elevated temperature. This is referred to as the cold stage and is characterised by a vigorous shivering. It is caused by the rupture of the infected erythrocytes and the release of merozoites which further affects the new RBC.
So, the correct answer is option D.

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