A person suffering from malaria experiences chills when

Exoerythrocytic cycle is completed

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Signet ring stage is formed

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RBCs rupture and haemozoin granules are released

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All of the above

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Solution

The correct option is A RBCs rupture and haemozoin granules are released
During the trophic period, the parasite ingests the host cytoplasm and breaks down the haemoglobin into amino acids. A by-product of the hemoglobin digestion is the malaria pigment or haemozoin. The host inflammatory reactions like fever are initiated by periodic rupture of infected RBCs, which release haemozoin and other parasitic metabolic wastes.

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