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Question

A physician wishes to prepare a buffer solution at pH=3.58 that efficiently resists a change in pH yet contains only small concentration of buffering agents. Which one of the following weak acids together with its sodium salt would be best to use?

A
m-chlorobensoic acid (pKa=3.98)
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B
p-chlorobenzoic acid (pKa=4.41)
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C
2,5-dihydroxybenzoic acid (pKa=2.97)
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D
Acetoacetic acid (pKa=3.58)
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Solution

The correct option is C 2,5-dihydroxybenzoic acid (pKa=2.97)

2,5-dihydroxybenzoic acid (pKa=2.97) is the best weak acid which has less pH than the desired buffer solution,so 2,5-dihydroxybenzoic acid do not change the pH of resulting solution.

Hence option C is correct.


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