Question

A piece of nucleotide used to detect a gene of complementary sequence by hybridising with it, is called

• A. DNA probe
• B. protein probe
• C. cDNA
  
• D. All of the above
  

Answer 1

The correct option is A DNA probe

The complementary binding of DNA/RNA and affinity binding of antibodies are used in hybridisation to detect sequences of interest and protein in a given sample.

DNA probes are stretches of single-stranded DNA used to detect the presence of complementary nucleic acid sequences (target sequences) by hybridization. DNA probes are usually labelled, for example with radioisotopes, epitopes, biotin or fluorophores to enable their detection.