The correct option is C Deficiency of iodine in diet
Iodine is essential for the normal rate of hormone synthesis in the thyroid. Deficiency of iodine in diet results in hypothyroidism and enlargement of the thyroid gland, commonly called goitre.
Hypothyroidism during pregnancy causes defective development and maturation of the growing baby leading to stunted growth (cretinism), mental retardation, low intelligence quotient, abnormal skin, deaf-mutism, etc.