A segment of DNA contains 1200 nucleotides, of which 200 have adenine base. How many cytosine bases are present in this segment of DNA?
A
100
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B
200
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C
400
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D
800
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Solution
The correct option is C 400
According to Chargaff's rule, the proportion of adenine is equal to thymine and the proportion of cytosine is equal to guanine because they are complementary bases.
There are 200 adenine bases. The number of thymine bases will be equal to adenine which is 200 bases.
The total number of bases is 1200. So, the remaining bases are 1200-(200+200)= 800.
From the 800 bases, the number of cytosine and guanine will be the same, which is equal to 400 bases each.