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Question

A segment of DNA contains 1200 nucleotides, of which 200 have adenine base. How many cytosine bases are present in this segment of DNA?

A
100
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B
200
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C
400
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D
800
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Solution

The correct option is C 400
  • According to Chargaff's rule, the proportion of adenine is equal to thymine and the proportion of cytosine is equal to guanine because they are complementary bases.
  • There are 200 adenine bases. The number of thymine bases will be equal to adenine which is 200 bases.
  • The total number of bases is 1200. So, the remaining bases are 1200-(200+200)= 800.
  • From the 800 bases, the number of cytosine and guanine will be the same, which is equal to 400 bases each.
Thus, the correct answer is option C.

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