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Question
A strand of DNA has following base sequence 3' AAAAGTGACTAGTGA 5'. On transcription, it produces an mRNA which of the following anticodon of tRNA recognizes the third codon of this mRNA?
A strand of DNA has following base sequence 3' AAAAGTGACTAGTGA 5'. On transcription, it produces an mRNA which of the following anticodon of tRNA recognizes the third codon of this mRNA?
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Solution
The correct option is C GAC
If a strand of DNA has the following base sequence 3' AAAAGTGACTAGTGA 5', after transcription the mRNA formed will have the sequence 5' UUUUCACUGAUCACU 3'. tRNA are adapter molecules that on one hand read the code and on the other hand would bind to specific amino acids. tRNA has an anticodon loop that has bases complimentary to the code and it binds to codon on the mRNA. The codon anticodon pairing is specific and there are specific tRNAs for each amino acid. There are no tRNAs for stop codons. For initiation, there is another specific tRNA referred to as initiator tRNA. tRNA also has amino acid acceptor end to which it binds to amino acids. The actual structure of tRNA is a compact molecule which looks like an inverted L. But the secondary structure of tRNA looks like a clover leaf. To recognize the third codon of the mRNA produced (as mentioned above in the answer) which is 5' CUG 3' tRNA with a specific anticodon sequence of 3' GAC 5' would be required. Thus, the correct option is C
If a strand of DNA has the following base sequence 3' AAAAGTGACTAGTGA 5', after transcription the mRNA formed will have the sequence 5' UUUUCACUGAUCACU 3'. tRNA are adapter molecules that on one hand read the code and on the other hand would bind to specific amino acids. tRNA has an anticodon loop that has bases complimentary to the code and it binds to codon on the mRNA. The codon anticodon pairing is specific and there are specific tRNAs for each amino acid. There are no tRNAs for stop codons. For initiation, there is another specific tRNA referred to as initiator tRNA. tRNA also has amino acid acceptor end to which it binds to amino acids. The actual structure of tRNA is a compact molecule which looks like an inverted L. But the secondary structure of tRNA looks like a clover leaf. To recognize the third codon of the mRNA produced (as mentioned above in the answer) which is 5' CUG 3' tRNA with a specific anticodon sequence of 3' GAC 5' would be required. Thus, the correct option is C
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