A tumour in the adrenal zona glomerulosa can cause hyper secretion of hormone produced in that region. Which of the following might you expect to find in a patient with such a tumour?
A
Increased blood sodium levels
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B
Increased blood glucose levels
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C
Decreased blood calcium levels
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D
Increased dehydration
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Solution
The correct option is B Increased blood sodium levels The outermost layer of adrenal gland, the zona glomerulosa is the main site for production of mineralocorticoids, mainly aldosterone.
Aldosterone exerts its effects on the distal convoluted tubule and collecting duct of the kidney, where it causes increased reabsorption of sodium and increased excretion of both potassium and hydrogen ions. Hence, a tumour in the adrenal zona glomerulosa can cause hypersecretion of aldosterone hormone, leading to increased blood sodium levels.