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Question

A useful drug that damages gastric mucosa, if taken along with alcohol is

A
Valium
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B
Anthistamine
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C
Asprin
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D
Morphine
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Solution

The correct option is B Asprin
Gastritis occurs when there is an imbalance between the acid, and the mucous produced, and the acid manages to erode and damage the stomach lining. Aspirin, which inhibits cyclooxygenase, is rapidly deacetylated to salicylate. Salicylate is toxic to cells and affects mucosal barrier function, reduces cytosolic adenosine triphosphate, stimulates sodium transport, and increases proton dissipation from surface epithelial cells.
So the correct answer is 'Asprin'.

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