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Question

(a) What are essential and non-essential amino acids? Give two examples of each type.

(b) Define the following as related to proteins

(i) Peptide linkage (ii) Primary structure (iii) Denaturation.

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Solution

(a) Amino acids are classified essential and non-essential amino acids, Non-essential amino acids can

be made by the body.

Ex: Glycine, alanine

Essential amino acids cannot be made by human body so must be given in the diet.

Ex: Valine, leucine

(b) (i) Peptide linkage

Amino acids are connected to each other by peptide bond or peptide linkage to form proteins (polymer)

(ii) Primary structure: Polypeptide chain in protein has amino acids linked with each other in a particular sequence and this sequence is called primary structure.

(iii) Denaturation: When a protein in its native form is subjected to physical change like change in temperature or chemical change like change in pH, the hydrogen bonds are disturbed. The globules unfold and helix get uncoiled and protein loses its biological activity. This is called denaturation.


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