Question

A woman has a child with Klinefelter's syndrome. Number of barr bodies present in the child is?

• A. One
• B. Two
• C. Three
• D. Any of the above

Answer 1

The correct option is D Any of the above

Klinefelter’s syndrome is aneuploid condition marked by the presence of one or more extra chromosomes in a male (44+XXY/ 44+XXXY/ 44+XXXXY). As we know that human females have two copies of X-chromosome while the male has the only single copy. To compensate the dosage of X-linked genes in human male and female, one X-chromosome in females is deactivated and is present as darkly stained body near nuclear envelope. The number of Barr bodies is always one less than the total number of X chromosomes. A human male with Klinefelter’s syndrome, 44+XXY/ 44+XXXY/ 44+XXXXY, can have 1, 2 or 3 Barr bodies, depending on the number of X-chromosome. Options A, B and C are correct answers.

So, the correct answer is 'one,two or three'.