A woman with blood group O married a man with blood group AB. Show the possible blood groups of the progeny. List the alleles involved in this inheritance.

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Solution

ABO blood group system has three alleles, A, B and O. Any person has two alleles of these three in any combinations. In the above case, women with blood group O marries a man with blood group AB.
Hence, the parents have the following genotypes:
Mother - I^O I^O, Father- I^A I^B
Using the Punnet square technique, the possible blood groups in the progeny are as given:

I^O I^O
I^A I^A I^O I^A I^O
I^B I^B I^O I^B I^O
Hence, the possible genotypes are I^A I^O and I^B I^O
Therefore possible phenotypes are- Blood Group A and Blood group B.

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