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Question

A woman with normal vision, but whose father was colour bind, marries a colour blind man. Suppose that the fourth child of this couple was a boy. This boy -

A
Must have normal colour vision
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B
May be colour blind or may be normal vision
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C
Will be partially colour blind since he is heterozygous for the colour blind mutant allele.
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D
Must be colour blind
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Solution

The correct option is B May be colour blind or may be normal vision
Gametes 22A+x 22A+Y
22A+X 22AA+Xx- carrier female 22AA+XY- normal male
22A+x 22AA+xx- diseased female 22AA+xY- diseased male
The woman has normal vision but her father was colour blind so she should be the carrier to the disease as Colour blindness is an X-Linked recessive disorder.
So, the genotype of the woman should be- 22AA+Xx (where 'X' represent normal sex chromosome while 'x' represents colour blinded).
The genotype of man to be colourblind should be: 22AA+xY
So, the cross between 22AA+Xx X 22AA+xY is shown in the table.
The probability of Male child to be colourblind will 50% and the ratio of diseased to a normal male child is 1:1.
So, the correct answer is 'Maybe colour blind or maybe normal vision'.
So the correct option is B.

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