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Question

Acceptor of acetyl CoA in Krebs cycle is

A
malic acid
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B
fumaric acid
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C
𝝰- ketoglutaric acid
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D
oxaloacetic acid
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Solution

The correct option is D oxaloacetic acid
Krebs’ cycle starts with the condensation of acetyl group (acetyl CoA) with oxaloacetate (4- carbon compound) in the presence of a condensing enzyme citrate synthase to form a tricarboxylic, 6- ­carbon compound called citric acid. It is the 1st product of Krebs cycle. CoA is liberated. Hence oxaloacetic acid is the acceptor of acetyl CoA in Krebs cycle.

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