Question

According to the induced fit theory of enzyme action,

• A. substrate induces a conformational change in enzyme
• B. substrate changes its shape after binding
• C. conformational change takes place in substrate
• D. there is no conformational change in enzyme

Answer 1

The correct option is A substrate induces a conformational change in enzyme

There are two models which describe the binding of the substrate to the enzyme: Lock and key model and induced-fit model.

According to the induced-fit theory, the active site of the enzyme does not initially exist in a shape that is complementary to the substrate. But it is induced to assume the complementary shapes according to the substrate configuration so that there is a precise ‘fit’ between enzyme and substrate.