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Induced Fit Theory

According to ...

Question

According to the Koshland induced fit hypothesis, the binding of substrate to enzyme may bring a change in

A

Substrate

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B

Enzyme

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C

Both substrate and enzyme

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D

None of them

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Solution

The correct option is B
Enzyme

The correct option is B
Explanation of the correct option:
According to the induced fit theory by Daniel Koshland, binding of substrate to the enzyme brings a conformational change in the enzyme to either enhance or inhibit its activity.
The active site keeps changing its shape until it is bound to the substrate, the final binding gives a proper shape to the enzyme.
Though, it doesn't create any difference in the shape of the substrate.
Final answer: According to the Koshland induced fit hypothesis, the binding of substrate to enzyme may bring a change in enzyme.

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Similar questions

Q. According to the induced fit hypothesis, which of the active site of enzymes brings about the catalytic changes of the substrate?

Q. The binding of the substrate induces the enzyme to alter its shape fitting more tightly around the substrate.

Q. Arrange the steps of catalytic action of an enzyme in order and choose the right option.

(i)

Enzyme releases products of reaction and the enzyme is free to bind to another substrate.

(i i)

Active site of enzyme is in close proximity of substrate and breaks the chemical bonds of substrate.

(i i i)

Binding of substrate induces enzyme to alter its shape fitting more tightly around substrate.

(i v)

Substrate binds to active site of enzyme fitting into active site.

Q. Identify the wrong statemets.

(a)

The substrate binds to active site of enzyme and not fitting into active site

(b)

The binding of substrate induces the enzyme to alter its shape

(c)

Chemical bonds of substrate break down not to form new enzyme-product complex

(d)

The enzyme releases the products of the reaction and runs through catalytic cycle once again

Q. Identify the wrong statements:

(A) The substrate binds to the active site of the enzyme and not fitting into the active site.
(B) The binding of the substrate induces the enzyme to alter its shape.
(C) Chemical bonds of the substrate does not break down to form new enzyme-product complex.
(D) The enzyme releases the reaction and runs through the catalytic cycle once again.

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