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Question

According to the Koshland induced fit hypothesis, the binding of substrate to enzyme may bring a change in


A

Substrate

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B

Enzyme

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C

Both substrate and enzyme

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D

None of them

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Solution

The correct option is B

Enzyme


The correct option is B

Explanation of the correct option:

  1. According to the induced fit theory by Daniel Koshland, binding of substrate to the enzyme brings a conformational change in the enzyme to either enhance or inhibit its activity.
  2. The active site keeps changing its shape until it is bound to the substrate, the final binding gives a proper shape to the enzyme.
  3. Though, it doesn't create any difference in the shape of the substrate.

Final answer: According to the Koshland induced fit hypothesis, the binding of substrate to enzyme may bring a change in enzyme.


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